Company Profile
Pharmacylics
Company Overview
Pharmacyclics Inc. is a clinical-stage biopharmaceutical company focused on discovering and developing innovative small-molecule drugs for the treatment of cancer and immune mediated diseases.
Building a Pipeline of Novel Drugs
Our pharmaceutical drug development candidates are synthetic small-molecules designed to target key biochemical pathways involved in human diseases with critical unmet needs. Currently we have three candidates in clinical development and several molecules in preclinical development.
Ibrutinib (PCI-32765), first-in-human, oral therapy that is a selective, irreversible Bruton's tyrosine kinase (BTK) inhibitor being investigated in B-cell hematologic malignancies.
PCI-27483, a subcutaneously administered Factor VIIa inhibitor targeting tissue factor expressing tumors in oncology (being investigated in pancreatic cancer).
Abexinostat hydrochloride (PCI-24781), an oral Histone Deacetylase (HDAC) inhibitor being investigated in oncology applications, such as lymphomas and solid tumor malignancies.
BTK Inhibitor compounds for autoimmune diseases in preclinical development.
Isoform selective HDAC8 inhibitors in preclinical development.
An Exciting Today. An Even More Exciting Tomorrow.
At Pharmacyclics, Inc., we are validating and fast-forwarding a new era of potentially patient-friendly therapies. How? By setting a higher bar for drugs through a target-based approach to medicine. With three molecules in clinical development and several pre-clinical molecules, our current pipeline of products shows vast potential.
Every day at Pharmacyclics, our team takes another step forward in moving these potential life-changing investigational products through the research pipeline and clinical development, with the ultimate goal of improving and prolonging the lives of people living with cancer and autoimmune disorders.
We are currently seeking world-class individuals to join us as we work towards bringing this new era of potentially patient-friendly therapies. If selected, you will join a team of leading minds from the world of oncology. Whatever the role, each of our employees is meaningfully contributing to this company's quest to make a significant difference in people's lives.
If you are ready to share our passion for developing patient-friendly therapies and to break new ground with a company built on sound science and a long-term plan for operational viability, then we'd like to hear from you. Begin your search for current professional and support positions below.
